- Andreatini R, Sartori VA, Seabra ML, Leite JR. Effect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo-controlled pilot study. Phytother Res 2002;16:650-4.
- Bourin M, Bougerol T, Guitton B, Broutin E. A combination of plant extracts in the treatment of outpatients with adjustment disorder with anxious mood: controlled study versus placebo. Fundamental and Clinical Pharmacology 1997;11(2):127-32.
- Cropley M, Cave Z, Ellis J, Middleton RW. Effect of kava and valerian on human physiological and psychological responses to mental stress assessed under laboratory conditions. Phytother Res 2002;16:23-7.
- Delsignore R, Orlando S, Costi D, Baroni MC, Butturini U. Clinical comparative evaluation of a stabilized valeriana extract and placebo. A Folha Medica 1992;104(5):191-6.
- Hadley S, Petry JJ. Valerian. Am Fam Physician 2003;67:1755-8
- Hattesohl M, Feistel B, Sievers H, Lehnfeld R, Hegger M, Winterhoff H. Extracts of Valeriana officinalis L. s.l. show anxiolytic and antidepressant effects but neither sedative nor myorelaxant properties. Phytomedicine. 2008;15(1-2):2-15.
- Kohnen R, Oswald WD. The effects of valerian, propranolol, and their combination on activation, performance, and mood of healthy volunteers under social stress conditions. Pharmacopsychiatry 1988;21:447-8.
- Muller D, Pfeil T, von den Driesch V. Treating depression comorbid with anxiety - results of an open, practice-oriented study with St John's wort WSu 5572 and valerian extract in high doses. Phytomedicine 2003;10:25-30.
- Muller SF, Klement S. A combination of valerian and lemon balm is effective in the treatment of restlessness and dyssomnia in children. Phytomedicine 2006;13(6):383-7.
- Alino J, Gutierrez J, Iglesias M. 5-Hydroxytryptophan (5-HTP) and a MAOI (nialamide) in the treatment of depression. A double blind controlled study. International Pharmacopsychiatry 1976;11(1):8-15.
- Angst J, Woggon B, Schoepf J. The treatment of depression with L-5-Hydroxytryptophan versus imipramine. Results of two open and one double-blind study. Archiv fuer Psychiatrie und Nervenkrankheiten 1977;224(2):175-86.
- Jorm AF, Christensen H, Griffiths KM, Parslow RA. Effectiveness of complementary and self-help treatments for anxiety disorders. Med J Aust 2004;181(7 Suppl):S29-46.
- Kline N, Sacks W, Simpson G. Further studies on one day treatment of depression with 5-HTP. American Journal of Psychiatry 1964;121:379-81.
- Kahn RS, Westenberg HG, Verhoeven WM, Gispen-de Wied CC, Kamerbeek WD. Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo. International Clinical Psychopharmacology 1987;2(1):33-45.
- Meltzer H, Perline R, Tricou B, Loewe M, Robertson A. Effect of 5-Hydroxytryptophan on serum cortisol levels in major affective disorders II Relation to suicide. Archives of General Psychiatry 1984;41(4):379-87.
- Schruers K, van Diest R, Overbeek T, Griez E. Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients. Psychiatry Res 2002;113(3):237-43.
- Shaw K, Turner J, Del Mar C. Tryptophan and 5-hydroxytryptophan for depression. Cochrane Database Syst Rev 2002;(1):CD003198.
- Van Praag HM, Korf J. 5-Hydroxytryptophan as antidepressant: The predictive value of the probenecid test. Psychopharmacology Bulletin 1972;8(4):34-5.
- Calabrese C, Gregory WL, Leo M, Kraemer D, Bone K, Oken B. Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial. J Altern Complement Med. 2008;14(6):707-13.
- Ernst, E. Herbal remedies for anxiety - a systematic review of controlled clinical trials. Phytomedicine 2006;13(3):205-208.
- Baldewicz T, Goodkin K, Feaster DJ, Blaney NT, Kumar M, Kumar A, Shor-Posner G, Baum M. Plasma pyridoxine deficiency is related to increased psychological distress in recently bereaved homosexual men. Psychosom Med 1998;60(3):297-308.
- Bell IR, Edman JS, Morrow FD, Marby DW, Mirages S, Perrone G, Kayne HL, Cole JO. B complex vitamin patterns in geriatric and young adult in patients with major depression. J Am Geriatr Soc 1991;39(3):252-7.
- Bermond P. Therapy of side effects of oral contraceptive agents with vitamin B6. Acta Vitaminol Enzymol 1982;4(1-2):45-54.
- De Souza MC, Walker AF, Robinson PA, Bolland K. A synergistic effect of a daily supplement for 1 month of 200 mg magnesium plus 50 mg vitamin B6 for the relief of anxiety-related premenstrual symptoms: a randomized, double-blind, crossover study. J Womens Health Gend Based Med 2000;9(2):131-9.
- Edwin E, Holten K, Norum FR, Schrumpf A, Skaug OE: Vitamin B12 hypovitaminosis in mental diseases. Acta Med Scand 1965;177:689-699.
- Frazer CJ, Christensen H, Griffiths KM. Effectiveness of treatments for depression in older people. Med J Aust 2005;182(12):627-32.
- Hasanah CI, Khan UA, Musalmah M, Razali SM. Reduced red-cell folate in mania. J Affect Disord 1997;46(2):95-9.
- Kalinin VV, Zheleznova EV, Rogacheva TA, Sokolova LV, Polianski? DA, Zemlianaia AA, Nazmetdinova DM. A use of Magne-B6 in the treatment of anxiety-depressive states in patients with epilepsy. Zh Nevrol Psikhiatr Im S S Korsakova 2004;104(8):51-5.
- Kaplan BJ, Simpson JS, Ferre RC, Gorman CP, McMullen DM, Crawford SG. Effective mood stabilization with a chelated mineral supplement: an open-label trial in bipolar disorder. J Clin Psychiatry. 2001;62(12):936-44.
- McCarty MF. High-dose pyridoxine as an 'anti-stress' strategy. Med Hypotheses 2000;54(5):803-7.
- Reid SD. Pseudodementia in a twenty-one-year-old with bipolar disorder and vitamin B12 and folate deficiency. Journal of West Indian Medicine 2000;49(4):347-8.
- Young SN. Folate and depression--a neglected problem. J Psychiatry Neurosci 2007;32(2):80-2.
- Ito K, Nagato Y, Aoi N, et al. Effects of L-theanine on the release of alpha-brain waves in human volunteers. Nippon Nogeikagaku Kaishi 1998;72:153-157.
- Juneja, LR, DC Chu, T Okubo, Y Nagato, H Yokogoshi L-theanine-a unique amino acid of green tea and its relaxation effect in humans. Trends in Food Science & Technology 1999;10(6-7):199-204.
- Kakuda T, Nozawa A, Unno T, et al. Inhibiting effects of theanine on caffeine stimulation evaluated by EEG in the rat. Biosci Biotechnol Biochem 2000;64:287-293.
- Kimura, K, M Ozeki, LR Juneja, H Ohira L-Theanine reduces psychological and physiological stress responses Biological Psychology 2007;74(1):39-45.
- L-theanine . Monograph. Altern Med Rev 2005;10(2):136-8.
- Lu K, Gray MA, Oliver C, Liley DT, Harrison BJ, Bartholomeusz CF, Phan KL, Nathan PJ. The acute effects of L-theanine in comparison with alprazolam on anticipatory anxiety in humans. Hum Psychopharmacol 2004;19(7):457-65.
- Rogers PJ, Smith JE, Heatherley SV, Pleydell-Pearce CW. Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together. Psychopharmacology (Berl) 2008;195(4):569-77.
- Yokogoshi H, Kobayashi M, Mochizuki M, Terashima T. Effect of theanine, rglutamylethylamide, on brain monoamines and striatal dopamine release in conscious rats. Neurochem Res 1998;23:667-73.
- Yokogoshi H, Kato Y, Sagesaka YM, et al. Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats. Biosci Biotechnol Biochem1995;59:615-8.
- Akhondzadeh S, Naghavi HR, Vazirian M, Shayeganpour A, Rashidi H, Khani M. Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam. Journal of Clinical Pharmacy and Therapeutics 2002;26(5):363-7.
- Barbosa PR, Valvassori SS, Bordignon CL Jr, Kappel VD, Martins MR, Gavioli EC, Quevedo J, Reginatto FH. The aqueous extracts of Passiflora alata and Passiflora edulis reduce anxiety-related behaviors without affecting memory process in rats. J Med Food 2008;11(2):282-8.
- Bourin M, Bougerol T, Guitton B, Broutin E. A combination of plant extracts in the treatment of outpatients with adjustment disorder with anxious mood: controlled study versus placebo. Fundamental & Clinical Pharmacology 1997;11(2):127-32.
- Brown E, Hurd NS, McCall S, Ceremuga TE. Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat. AANA J 2007;75(5):333-7.
- Dhawan K, Dhawan S, Chhabra S. Attenuation of benzodiazepine dependence in mice by a tri-substituted benzoflavone moiety of Passiflora incarnata Linneaus: a non-habit forming anxiolytic. J Pharm Pharm Sci 2003;6(2):215-22.
- Dhawan K, Kumar S, Sharma A. Anxiolytic activity of aerial and underground parts of Passiflora incarnata. Fitoterapia 2001;72(8):922-6.
- Dhawan K, Kumar S, Sharma A. Anti-anxiety studies on extracts of Passiflora incarnata Linneaus. J Ethnopharmacol 2001;78(2-3):165-70.
- Ernst E. Herbal remedies for anxiety - a systematic review of controlled clinical trials. Phytomedicine 2006;13(3):205-8.
- Krenn L. Passion Flower (Passiflora incarnata L.)--a reliable herbal sedative. Wien Med Wochenschr 2002;152(15-16):404-6.
- Miyasaka LS, Atallah AN, Soares BG. Passiflora for anxiety disorder. Cochrane Database Syst Rev 2007;(1):CD004518.
- Mori A, Hasegawa K, Murasaki M, Yamauchi T, et al.Clinical Evaluation of Passiflamin (passiflora extract) on neurosis - multicenter double blind study in comparison with mexazolam. Clinical Evaluation 1993;21:383-440.
- Movafegh A, Alizadeh R, Hajimohamadi F, Esfehani F, Nejatfar M. Preoperative oral Passiflora incarnata reduces anxiety in ambulatory surgery patients: a double-blind, placebo-controlled study. Anesth Analg 2008;106(6):1728-32.
- Awad R, Levac D, Cybulska P, Merali Z, Trudeau VL, Arnason JT. Effects of traditionally used anxiolytic botanicals on enzymes of the gamma-aminobutyric acid (GABA) system. Can J Physiol Pharmacol 2007;85(9):933-42.
- Kakuta, H., Yano-Kakuta, E. and Moriya, K. Psyxhological and physiological effects in humans of eating chamomile jelly. Acta Hort (ISHS) 2007;749:187-92.
- McKay, Diane L., Jeffrey B. Blumberg A Review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.) Phytotherapy Research 2006;20(7):519-30.
- De Souza MC, Walker AF, Robinson PA, Bolland K. A synergistic effect of a daily supplement for 1 month of 200 mg magnesium plus 50 mg vitamin B6 for the relief of anxiety-related premenstrual symptoms: a randomized, double-blind, crossover study. J Womens Health Gend Based Med 2000;9(2):131-9.
- Grases G, Purez-Castellu JA, Sanchis P, Casero A, Perellu J, Isern B, Rigo E, Grases F. Anxiety and stress among science students. Study of calcium and magnesium alterations. Magnes Res 2006;19(2):102-6.
- Fromm L, Heath DL, Vink R, Nimmo AJ. Magnesium attenuates post-traumatic depression/anxiety following diffuse traumatic brain injury in rats. J Am Coll Nutr 2004;23(5):529S-533S.
- Hanus M, Lafon J, Mathieu M. Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate anxiety disorders. Curr Med Res Opin 2004;20(1):63-71.
- Jacka FN, Overland S, Stewart R, Tell GS, Bjelland I, Mykletun A. Association between magnesium intake and depression and anxiety in community-dwelling adults: the Hordaland Health Study. Aust N Z J Psychiatry 2009;43(1):45-52.
- Poleszak E, Szewczyk B, Kedzierska E, Wla? P, Pilc A, Nowak G. Antidepressant- and anxiolytic-like activity of magnesium in mice. Pharmacol Biochem Behav 2004;78(1):7-12.
- Recarte Garcua Andrade C, del Castillo Rueda A, Torres Segovia F. Anxiolytic effect of magnesium. An Med Interna 1991;8(11):576.
- Seelig MS. Consequences of magnesium deficiency on the enhancement of stress reactions; preventive and therapeutic implications (a review). J Am Coll Nutr 1994;13(5):429-46.
- Spasov AA, Iezhitsa IN, Kharitonova MV, Kravchenko MS. Depression-like and anxiety-related behaviour of rats fed with magnesium-deficient diet. Zh Vyssh Nerv Deiat Im I P Pavlova 2008;58(4):476-85.